Bioconjugated Fluorescent Nanodiamond

Bioconjugated fnd images banner largest test colored

 

 

 

Explore the limits of biology with limitless fluorescence.

 

Time-lapse of blood clots specifically labeled with fluorescent nanodiamond (top) or phycoerythrin (PE) (bottom). PE quickly degrades, while the fluorescent nanodiamond signal remains constant.

 

Biofunctionalized fluorescent nanodiamonds are infinitely photostable labels for fluorescent and multiphoton microscopy applicable to cellular tracking and long-term observation of biological processes in the same fields of view in live cell-imaging and fixed cells. Protein, antibody, biologically active organic molecules, and custom functionalizations are possible. We provide nanodiamonds with nitrogen-vacancy (NV) centers with red-to-near-infrared fluorescence, NVN centers with green fluorescence, and novel particles available only at Adamas with a combination of NV and NVN centers within a single particle with visual yellow fluorescence. Fluorescence from NV centers can be magnetically modulated providing a means to eliminate the fluorescent background by image subtraction and to significantly enhance the signal-to-noise ratio. This property can be very useful in future biosensing applications, for example in clinical diagnostics such as lateral flow assays (LFA). Relevant applications also include super-resolution microscopy, multiphoton microscopy, time-gated microscopy and correlative microscopy.

 

Red Fluorescent Nanodiamond Functionalized with Antibodies


Product NV Content Concentration and Solvent Amount  Average Size Price SKU Buy Now

 

100 nm Fluorescent Nanodiamond
Goat AntiRabbit 

~3 ppm NV

1 mg/mL in PBS with 0.1% BSA as a stabilizer

 

500 ug      

 

100 nm

 

$637

 

NDNV100nmOPGantiRabbit500ug
 

 

100 nm Fluorescent Nanodiamond
Goat AntiMouse

~3 ppm NV

1 mg/mL in PBS with 0.1% BSA as a stabilizer

 

500 ug 

 

100 nm

 

$637

 

NDNV100nmOPGantiMouse500ug
 

Other Red Functionalized Fluorescent Nanodiamond 

Bioconjugated Green FND and Red FND products of different sizes are available as a custom order. Please contact us to order.

Product

NV Content

 Concentration and Solvent Amount  Particle Size Price SKU Buy Now

 

40 nm Red Fluorescent Nanodiamond
with Biotin

~2 ppm NV

1 mg/mL in DI water

 

2 mg 

 

40-45 nm

 

$540

 

NDNV40nmHibiotin2mg
 
 

 

40 nm Red Fluorescent Nanodiamond
with Streptavidin 

~2 ppm NV

1 mg/mL in PBS with 0.1% BSA as a stabilizer

 

2 mg 

 

40-45 nm

 

$651

 

NDNV40nmHiSA2mg
 

 

100 nm Red Fluorescent Nanodiamond
with Biotin

~3 ppm NV

1 mg/mL in Di water

 

2 mg 

 

100 nm

 

$503

 

NDNV100nmHibiotin2mg
 

 

100 nm Red Fluorescent Nanodiamond
with Streptavidin

~3 ppm NV

1 mg/mL in PBS with 0.1% BSA as a stabilizer

 

2 mg

 

 

100 nm

 

$613

 

NDNV100nmHiSA2mg
 

 

100 nm Red Fluorescent Nanodiamond
with Biotin

~3 ppm NV

1 mg/mL in DI water

 

10 mg

 

100 nm

 

$1167

 

NDNV100nmHibiotin10mg
 

 

100 Red Fluorescent Nanodiamond  aminated with ethylenediamine 

~3ppm NV

1 mg/mL in DI water

 

2 mL

 

100 nm

 

$798

 

100nmFND-PG-EDA2mL
 

 

140 nm Red Fluorescent
Nanodiamond with Polyglycerol

~3ppm

1 mg/mL in DI water

 

2 mL

 

140 nm

 

$337

 

NDNV140nmHiPG2mg
 

Green Functionalized Fluorescent Nanodiamond 

Product

NV Content

 Concentration and Solvent Amount  Particle Size Price SKU Buy Now

 

120 nm Green Fluorescent Nanodiamond
with Biotin

Trace amounts of NV centers

1 mg/mL in DI water

 

2 mg 

 

120 nm

 

$410

 

NDNVN120nmbiotin2mg
 

 

120 nm Green Fluorescent Nanodiamond
with Biotin

Spectrally pure: depleted from NV centers

1 mg/mL in DI water

 

2 mg 

 

120 nm

 

$526

 

NDNVN120nmSpPuBiotin2mg
 
 By purchasing this material, recipient agrees that the Material is to be used solely for testing purpose, and the Material will not be used in human subjects, in clinical trials, or for diagnostic purposes involving human subjects without the written consent of the Provider.